![]() His research field was bioinorganic and medicinal chemistry, responsive biomaterials, and electrochemically controlled interfaces. He was an author of 75 papers in peer-reviewed international journals (Hirsh-index 24), 3 book chapters, and 11 patents. Since 2008 he was an Associate Professor at the Department of Chemistry & Biomolecular Science of Clarkson University. He was a postdoctoral associate at the University of Oxford (1997-1999), a Lecturer at the Hebrew University of Jerusalem, and a Research Fellow at the National Institute of Diabetes, Digestive & Kidney Diseases (Bethesda, US). ![]() He co-authored over 20 peer-reviewed papers, 3 patents and 2 book chapters.Īrtem Melman received his PhD in Organic Chemistry from the Weizmann Institute of Science (Rehovot, Israel) in 1997. His research interests focus on development of novel functional nanomaterials and their applications for biosensing and environmental remediation, particularly using wearable bioelectronic devices. Presently, he is a Postdoctoral Research Associate at the Department of Chemistry & Biomolecular Science (Clarkson University). Then, in 2019, he received PhD in Chemistry from Clarkson University (Potsdam, NY. Daniel's study has resulted in various signal-triggered biomolecule release systems for biomedical and biotechnological applications.Īli Othman graduated with MSc in Chemistry from Jordan University of Science & Technology (Jordan) in 2008. His scientific interests are in the areas of “smart” signal-responsive materials, particularly based on alginate hydrogels. Melman at Clarkson University (Potsdam, NY, USA) where he is presently performing PhD study. After a short research stay at Universiteit Hasselt (Belgium) supported with Erasmus Scholarship, in 2019, Daniel joined groups of Prof. We believe that this review would stimulate innovative ideas and promote the research of this material, leading to novel functional materials with new and emerging applications.ĭaniel Massana Roquero graduated with Bachelor in Chemistry from Universidad Autónoma de Madrid (Spain) in 2019. In this review we highlight the state-of-the-art that concerns Fe 3+-cross-linked alginate hydrogels, encompassing from properties and synthesis to applications and future perspectives. In addition, the rich redox chemistry of Fe 3+ cations has been exploited for a wide range of applications, such as drug delivery, tissue engineering, or environmental remediation. ![]() The particular coordination of Fe 3+ cations has been found to be critical for mechanical strength, porosity, swelling and other physicochemical properties of the material rarely seen in other ionotropic alginate hydrogels. In recent years, the cross-linking of alginate with Fe 3+ cations has attracted increasing interest due to its extraordinary properties. However, alginate can produce hydrogels with a large number of divalent and trivalent cations. ![]() The vast majority of the research related to ionotropic alginate hydrogels has been conducted on Ca 2+-cross-linked alginate. Their biocompatibility and biodegradability have made them perfect candidates for biomedical applications such as tissue engineering and drug delivery. Ionotropic alginate hydrogels are versatile materials for a wide range of applications. ![]()
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